Book Details
Orange Code:56158
Paperback:266 pages
Publications:
Categories:
Sections:
1. Autocrine Transformation: Cytokine Model2. Signal Transduction Pathways: Cytokine Model .3. The Restriction Point of the Cell Cycle4. DNA-Damage-Independent Checkpoints from Yeast to Man5. The Regulation of p53 Growth Suppression6. Functional Interactions Between BRCA1 and the Cell Cycle7. The Role of FHIT in Carcinogenesis8. Hypoxia and Cell Cycle9. G2 Checkpoint and Anticancer Therapy10. p53, Apoptosis and Cancer Therapy11. Non-Apoptotic Responses to Anticancer Agents: Mitotic Catastrophe, Senescence and the Role of p53 and p2112. Small Molecule Inhibitors of Cyclin-Dependent Kinases13. Cell Cycle Molecular Targets and Drug Discovery
Description:
Cell Cycle Checkpoints and Cancer is about mechanisms of normal and cancer cell cycling, checkpoint control, and the link of mitogenic signalling and cell cycle machinery. Checkpoint mechanisms from yeast to man are addressed to allow a comprehensive understanding of the cell cycle. Applications to current and future anticancer therapies are discussed.
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