Nanoparticle-Based Drug Delivery in Cancer Treatment

1. The Advantages and Versatility of Carrier-Free Nanodrug and Nanoparticle Systems for Cancer Therapy
2. Strategies, Design, and Chemistry in Small Interfering RNA Delivery Vehicle Systems for Cancer Therapy
3. DNA/RNA Nanoparticles Structures for siRNA Delivery Applications
4. Codelivery in Nanoparticle-based siRNA for Cancer Therapy
5. Small Interfering RNAs, MicroRNAs, and NPs in Gynecological Cancers
6. Nanoparticle–Based RNA (siRNA) Combination Therapy Toward Overcoming Drug Resistance in Cancer
7. Advantages and Limitations of RNAi Delivery for Cancer Biological Therapeutics Imaging
8. Recent Development of Silica Nanoparticles as Delivery Biomedical Applications for Cancer Imaging and Therapy
9. Application of Carbon Nanotubes in Cancer Vaccines as Drug Delivery Tools
10. Development of Oligonucleotide Delivery, (siRNAs), and (miRNA) Systems for Anticancer Therapeutic Strategy Immunotherapy
11. Pharmacogenomics Synergistic Strategies Using a Chimerical Peptide for Enhanced Chemotherapy Based on ROS and DNA Nanosystem
12. Pharmacokinetics, Biodistribution, and Therapeutic Applications of Recently Developed siRNA and DNA Repair Genes Recurrence
13. Nanotechnologies Assemblies of siRNA and Chemotherapeutic Drugs Codelivered for Cancer Therapeutic Applications
14. Targeted Systemic Combinatorial Delivery of siRNA Polyplexes–Functional Quantum Dot-siRNA Nanoplexes
15. Recent Advances of Nanotechnologies for Cancer Immunotherapy Treatment

Careful choice of nanoparticles as targets and in drug delivery routes enhances therapeutic efficacy in cancer. Nanoparticle-Based Drug Delivery in Cancer Treatment discusses nanotechnological developments of interfering RNA-based nanoparticles and delivery vehicles, validated therapeutic RNAi-molecular target interactions, and explains the results of clinical and preclinical trials. The book also gives strategies which might be universal methods for constructing hybrid organic–inorganic nanomaterials and can be widely applied in biomedical field. Key Features:   Reviews recent advances of nanoparticle-mediated siRNA delivery systems and their application in clinical trials for cancer therapy.   Focuses on material platforms that establish NPs and both localized and controlled gene silencing.   Emphasizes the most promising systems for clinical translation.   Surveys progress in nanoparticle-based nanomedicine in cancer treatment.   Describes the most advanced of the non-viral nanocarriers for delivery of oligonucleotides to malignant blood cancer cells. This book is a valuable resource for researchers, professors, and students researching drug delivery, gene carriers, cancer therapy, nanotechnology, and nanomaterials.