The Zebrafish in Biomedical Research Biology, Husbandry, Diseases, and Research Applications

1. History of Zebrafish Research
2. Zebrafish Taxonomy and Phylogeny or Taxonomy and Phylogeny
3. Zebrafish Genetics
4. Geographic Range and Natural Distribution
5. Behavior of Wild Populations
6. Zebrafish in Biomedical Research: Head and Body: Anatomy
7. Establishing The Body Plan: The First 24 Hours of Zebrafish Development
8. Zebrafish Integumentary System
9. Zebrafish Pigmentation
10. Respiratory System
11. Skeletal System Morphophysiology
12. Zebrafish Myology
13. It Takes Guts: Development of the Embryonic and Juvenile Zebrafish Digestive System
14. The Zebrafish Cardiovascular System
15. Development of The Zebrafish Pronephric and Mesonephric Kidneys
16. The Reproductive System
17. Endocrine Systems
18. Zebrafish Nervous Systems
19. Immunology
20. Physiology: Hematology and Clinical Chemistry, Gas Exchange, and Regulatory Osmolality
21. Zebrafish in Biomedical Research: the Retina and Vision
22. The Mechanosensory Lateral Line System
23. Inner Ear and Hearing
24. Introduction to Zebrafish Husbandry
25. Aquatics Facility Design Considerations: Incorporating Aquatics into an Animal Facility
26. Aquatic Housing
27. Cleaning and Disinfection of Life Systems
28. Zebrafish Aquatic Systems: Preventative Maintenance and Troubleshooting
29. Water Quality For Zebrafish Culture
30. Recirculating Aquaculture Systems (RAS) for Zebrafish Culture
31. Zebrafish Breeding and Colony Management
32. Zebrafish Larviculture
33. Zebrafish Nutrition—Moving Forward
34. nesthesia, Analgesia, and Euthanasia of the Laboratory Zebrafish
35. Health Surveillance Programs
36. Importation and Quarantine
37. Export and Transportation of Zebrafish
38. Regulations, Policies and Guidelines Pertaining to the Use of Zebrafish in Biomedical Research
39. Water Quality and Idiopathic Diseases of Laboratory Zebrafish
40. Important Parasites of Zebrafish in Research Facilities
41. Bacterial and Fungal Diseases of Zebrafish
42. Viral Diseases
43. Nonexperimentally Induced Neoplastic and Proliferative Lesions in Laboratory Zebrafish
44. Special Procedures for Zebrafish Diagnostics
45. Zebrafish as a Model to Understand Vertebrate Development
46. Zebrafish as a Model for Revealing the Neuronal Basis of Behavior
47. Zebrafish as a Model to Understand Human Genetic Diseases
48. Zebrafish as a Model for Investigating Animal–Microbe Interactions
49. Targeted Editing of Zebrafish Genes to Understand Gene Function and Human Disease Pathology
50. Zebrafish as a Platform for Genetic Screening
51. Zebrafish as a Platform for Drug Screening

The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research.