1. The threat to the body: the role and requirements of the immune system2. The immediate response to infection: innate immunity and the inflammatory response3. Specific immune recognition: the antibody molecule4. T lymphocytes and MHC-associated recognition of antigen5. Generation of diversity: how do T and B cells generate so many different variants of their antigen receptors?6. Anatomy of the immune system7. Anatomical and cellular aspects of antibody production8. Effector mechanisms: dealing with pathogens in vivo (1) Antibody-mediated responses9. Effector mechanisms: dealing with pathogens in vivo (2) Cell-mediated immunity10. Immunological memory and vaccination11. Lymphocyte development and immunological tolerance12. Autoimmune diseases13. Allergy and other hypersensitivities14. AIDS15. Manipulating the immune system: transplantation and tumours