Essentials of Restenosis: For the Interventional Cardiologist

1. Pathophysiology and Diagnosis
2. Unraveling the Complex Process of Restenosis From Bench to Bedside
3. Epidemiology and Pathogenesis of Restenosis
4. Clinical Presentation of Restenosis
5. Pathological Anatomy of Restenosis
6. The Influence of Shear Stress on Restenosis
7. The Immune System in the Pathogenesis of Vascular Proliferative Disease
8. Animal Restenosis Models
9. The Genomics of Restenosis
10. Gene-Expression Profiling and Restenosis
11. Proteomics and Restenosis
12. Contribution of Circulating Progenitor Cells to Vascular Repair and Lesion Formation
13. Cell Cycle Regulators and Vascular Proliferative Diseases
14. Arterial Remodeling
15. The Role of eNOS in Vascular Diseases
16. The Use of Pressure Gradient in the Diagnosis of Restenosis
17. The Use of Radio Isotopes in the Diagnosis of Vascular Proliferative Disease
18. Magnetic Resonance Imaging for Restenosis
19. Coronary Imaging With Multislice Spiral Computed Tomography
20. Pharmacotherapy of Restenosis
21. Brachytherapy
22. Preclinical Data of Eluting Stents
23. Antisense and ODN Transcription Factors in the Treatment of Vascular Proliferative Disease
24. Cell Cycle Approaches to the Treatment of In-Stent Restenosis
25. Local Gene and Cell Delivery Devices

Leading interventional cardiologists, including Patrick Serruys, provide the gold-standard reference on the treatment of restenosis for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field, cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy.