Book Details
Orange Code:59964
Paperback:577 pages
Publications:
Categories:
Sections:
1. Visceral Leishmaniasis – Current Treatments and Needs2. Chemotherapy of Leishmaniasis: A Veterinary Perspective3. Pharmacological Metabolomics in Trypanosomes4. Drug Design and Screening by In Silico Approaches5. Computational Approaches and Collaborative Drug Discovery for Trypanosomal Diseases6. Interaction of Leishmania Parasites with Host Cells and its Functional Consequences7. Function of Glycosomes in the Metabolism of Trypanosomatid Parasites and the Promise of Glycosomal Proteins as Drug Targets8. Glyoxalase Enzymes in Trypanosomatids9. Trypanothione-Based Redox Metabolism of Trypanosomatids10. Thiol Peroxidases of Trypanosomatids11. Peroxynitrite as a Cytotoxic Effector Against Trypanosoma cruzi: Oxidative Killing and Antioxidant Resistance Mechanisms12. Selenoproteome of Kinetoplastids13. Screening Approaches Towards Trypanothione Reductase14. Redox-Active Agents in Reactions Involving the Trypanothione/Trypanothione Reductase-based System to Fight Kinetoplastidal Parasites15. Inhibition of Trypanothione Synthetase as a Therapeutic Concept16. New Developments in the Treatment of Late-Stage Human African Trypanosomiasis
Description:
This is the first resource to provide researchers in academia and industry with an urgently needed update on drug intervention against trypanosomatides. As such, it
covers every aspect of the topic from basic research findings, via current treatments to translational approaches in drug development and includes both human and livestock diseases. The outstanding editor and contributor team reads like a Who?s Who of the field, thus guaranteeing the outstanding quality of this ready reference.
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