Ocular Transporters in Ophthalmic Diseases and Drug Delivery

1. Roles of Corneal Epithelial Ion Transport Mechanisms in Mediating Responses to Cytokines and Osmotic Stress
2. Vitamin C Transport, Delivery, and Function in the Anterior Segment of the Eye
3. Mechanisms of Aqueous Humor Formation
4. Membrane Transporters
5. Lens Na+, K+-ATPase
6. Pathophysiology of Pericyte-containing Retinal Microvessels
7. Molecular Mechanisms of the Inner Blood-Retinal Barrier Transporters
8. Regulation of Transport in the RPE
9. Glucose Transporters in Retinal Pigment Epithelium Development
10. Ca2+ Channels in the Retinal Pigment Epithelium
11. Taurine Transport Pathways in the Outer Retina in Relation to Aging and Disease
12. P-Glycoprotein Expression and Function in the Retinal Pigment Epithelium
13. Glutamate Transporters and Retinal Disease and Regulation
14. The Emerging Significance of Drug Transporters and Metabolizing Enzymes to Ophthalmic Drug Design
15. Barriers in Ocular Drug Delivery
16. The Plasma Membrane Transporters and Channels of Corneal Endothelium

In this exceptionally important new work, a panel of distinguished authors discusses all the latest developments in the study of ocular transporters. Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volume discusses how transporters regulate the clarity of the cornea and lens, the movements of fluids across the ciliary epithelium and nutrients across the retinal pigment epithelium.